Keywords Bim;Grb10;SH2 domain;BH3 domain;yeast two hybrid;sub-cellular location;co-immunoprecipitation;site directed mutation;apoptosis;

• SH2结构域;BH3结构域;酵母双杂交;细胞定位;免疫共沉淀;定点突变;细胞凋亡;